Genetically Engineered Pig Models for Human Diseases
نویسندگان
چکیده
منابع مشابه
Current Progress of Genetically Engineered Pig Models for Biomedical Research
The first transgenic pigs were generated for agricultural purposes about three decades ago. Since then, the micromanipulation techniques of pig oocytes and embryos expanded from pronuclear injection of foreign DNA to somatic cell nuclear transfer, intracytoplasmic sperm injection-mediated gene transfer, lentiviral transduction, and cytoplasmic injection. Mechanistically, the passive transgenesi...
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ژورنال
عنوان ژورنال: Annual Review of Animal Biosciences
سال: 2013
ISSN: 2165-8102,2165-8110
DOI: 10.1146/annurev-animal-031412-103715